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KMID : 0371320080750060430
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Journal of the Korean Surgical Society
2008 Volume.75 No. 6 p.430 ~ p.433
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Successful Kidney Transplantation using Deceased Donor Kidney with Acute Tubular Necrosis
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Ju Man-Ki
Kim Beom-Seok
Jeong Hyeon-Joo
Kim Myoung-Soo
Kim Soon-Il
Kim Yu-Seun
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Abstract
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We present here a case of success kidney transplantation from a deceased donor who showed a serum creatinine level of 5.5 mg/dl. A 52-year-old Asian female with blood type O was determined to be brain death after a compressive craniectomy. Her post-operative course was fatal. She had experienced acute renal failure with oliguria, and these conditions had persisted for 3 days, and the serum creatinine level was elevated up to 5.5 mg/dl. The random urine creatinine, sodium and osmolarity levels were 17.6 mg/dl, 116 mmol/L and 346 mOsmol/L, respectively. However, the ultrasonographic and pathologic findings did not show any chronic structural abnormality in the kidneys. Two female patients with blood type O were transplanted with these donor kidneys. Both recipients experienced 2∼3 days of delayed graft function, but the graft function was fully recovered at 4∼5 day after transplantation. Both recipients were discharged with full-functioning grafts (1.1 and 0.9 mg/dl of serum creatinine, respectively). This shows that a deceased donor with reversible kidney damage, and even one showing a high serum creatinine level, can be acceptable for transplantation if the absence of chronic renal damage is confirmed by pathologic study. (J Korean Surg Soc 2008;75:430-433)
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KEYWORD
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Extended criteria donor, Serum creatinine, Reversible kidney damage
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